A Preliminary Note on the Treatment of 21 Cases of Kala-Azar with Sodium Antimony Gluconate. (With Special Reference to Its Suitability for Mass Administration on Tea Estates)
نویسندگان
چکیده
Introduction.?The senior writer, Burke (1943), made an appeal for an efficient successor to neostibosan (Bayer), this, preferably, to be a British product. What seems to be an almost perfect answer to that appeal?and indeed a British product?is the preparation stibatin (Glaxo Laboratories), or sodium antimony gluconate (antimony v-hexonate), a crystal-clear sterile solution containing 20 mg. of (pentavalent) antimony per c.cm. which, in collaboration with his assistants, he has recently (August 1943) tested thoroughly in tea estate practice. In such practice it is essential to have an anti-kala-
منابع مشابه
The Treatment of Kala-Azar with Sodium Antimony Gluconate (Stibatin). Further Observations on the Treatment of Thirty-Two Cases
couraging results, it was decided to a further extensive trial with this drug in certain hyperendemic kala-azar areas in the tea districts of Mangaldai, as an anti-kala-azar drug of such promising quality was indispensable, especially when, due to present war-time conditions, other pentavalent antimony compounds of proved value, e.g. solustibosan, neostibosan, etc., suitable for mass administra...
متن کاملThe Treatment of Kala-Azar with Sodium Antimony-V-Gluconate: Preliminary Observations *The work reported in this paper was undertaken under the Endowment Fund of the Calcutta School of Tropical Medicine, aided by a grant from the Indian Research Fund Association.
A pentavalent antimony compound (Sdt. 561, solustibosan, antimony-v-hexonate, containing 20 mg. of antimony per c.cm. of solution) , that made a stable solution and could be given intramuscularly, was first introduced b) Prof. H. Schmidt, the pioneer worker on pent*1' valent antimony compounds. Kikuth and Schmidt (1938) found that this compound possessed a marked curative action in the le*,' ma...
متن کاملEpidemiology of visceral leishmaniasis in India.
Kala-azar has re-emerged from near eradication. The annual estimate for the incidence and prevalence of kala-azar cases worldwide is 0.5 million and 2.5 million, respectively. Of these, 90% of the confirmed cases occur in India, Nepal, Bangladesh and Sudan. In India, it is a serious problem in Bihar, West Bengal and eastern Uttar Pradesh where there is under-reporting of kala-azar and post kala...
متن کاملImpact of amphotericin-B in the treatment of kala-azar on the incidence of PKDL in Bihar, India.
BACKGROUND & OBJECTIVE Of the two reservoirs of infection of kala-azar i.e., patients of kala-azar and post kala-azar dermal leishmaniasis (PKDL), PKDL provides easy access for the sandfly to pick up the parasites. In the last epidemic of 1977 in India, the importance of PKDL as a potential cause of increase in number of kala-azar cases was ignored. During recent years, we found an increase in ...
متن کامل